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Small stem cell ‘reservoirs’ can play an important role in hair regeneration

According to a new study by Elaine Fuchs, a researcher at Rockefeller University who identified a molecular coordinator used by the stem cells themselves, stem cells can also be used for tissue regeneration.

Skin, not just human skin, has an extraordinary ability to regenerate. This is possible due to the small “reservoirs” of stem cells that are embedded in small microenvironments called “niches.” These small tanks also play a supporting role: they inhibit the recovery process itself because too many tissues can cause various problems, including cancer.

Researchers have discovered a new component of these “niches” – lymphatic capillaries that transport immune cells and drain excess fluids, including any toxins. A network of capillaries forms around the stem cell niche within each hair follicle.

The hair follicle stem cells are the basis for the behavior of lymphatic capillaries: they produce molecules that activate and deactivate drainage and synchronize tissue regeneration.

According to Fuchs himself, this discovery can be useful, among other things, for creating new therapeutic purposes for all diseases associated with hair loss, as well as skin healing and wounds.

Links:

https://www.rockefeller.edu/news/26776-lymphatic-system-found-play-key-role-hair-regeneration/

https://science.sciencemag.org/content/early/2019/10/30/science.aay4509

Kelly Owen

Kelly majored in English Literature and is responsible for assisting in proofreading, editing and research, as well as for web design and the maintenance of this website. Beyond her outstanding writing skills, she has like the rest of us a passion for science and science reporting. She is an avid reader of many scientific journals and magazines, especially Scientific American. In her spare time she also enjoys reading fiction and hopes to complete her own novel in 2020.
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Kelly Owen